![]() The light source is a halogen tungsten lamp. It runs colorimetric and UV photometric methods at eight different wavelengths from 340 to 700 nm, with endpoint, kinetic, monochromatic, bichromatic, turbidimetric, sample, and reagent blanking options. The RX daytona from Randox (Kearneysville, WV is a compact benchtop analyzer (see Figure 1). An ISE is a sensor that determines the concentration of ions in a solution by measuring the current flow through an ion selective membrane. The other major analytical method is the use of ion selective electrodes to measure ions such as Na +, K +, Cl –, and Li +. The photometer shines light of the appropriate wavelength at the sample and measures the amount of light absorbed, which is directly correlated to the concentration of the analyte in the sample. The concentration of the analyte determines the strength of color produced. ![]() The sample is mixed with the appropriate reagent to produce a reaction that results in a color. The most common test method is photometry. Tests and analytical methodsįigure 1 – The RX daytona from Randox is a compact, fully automated benchtop clinical chemistry analyzer suitable for use in small- to medium-throughput laboratories. Other factors include sample handling, degree of automation, data management, operating costs, footprint, and whether the machine can handle micro volume samples. Your choice of chemical analyzer will depend on the types of test you wish to run and the throughput you require. Results are displayed on screen or sent to a printer or computer. Incubation time is allowed, if required then photometric or ion-selective electrode (ISE) testing determines the concentration of analyte. Reagents are added from an on-board refrigerated supply. A probe measures an aliquot of sample and places it into a reaction vessel. Samples are loaded into the machine and tests are programmed by the user. How does a clinical chemistry analyzer work?Īnalyzers are highly automated to maximize throughput, to improve user safety from biohazards, and to diminish the risk of cross-contamination. The results give clinicians feedback on toxicology and on renal, cardiac, and liver function. ![]() They are also used at the point-of-care, such as in physicians’ offices and patient bedsides.Īnalytes commonly include enzymes, substrates, electrolytes, specific proteins, drugs of abuse, and therapeutic drugs. Clinical chemistry analyzers are used in a variety of settings, including small clinics, research labs, and high-throughput hospital labs. ![]() Clinical chemistry analyzers run assays on clinical samples such as blood serum, plasma, urine, and cerebrospinal fluid to detect the presence of analytes relating to disease or drugs. ![]()
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